Thepen, Theo : rechercher sur Z-Library

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1

CD64 as a biomarker and therapeutic target in HAM/TSP and HTLV-1-associated Infective Dermatitis

Ricardo Khouri, George Soares, Gilvaneia Silva-Santos, Giselia Santana, Theo Thepen, Lourdes Farre, Achilea Bittencourt, Giovanni Lopez, Michael Talledo, Eduardo Gotuzzo, Anne-Mieke Vandamme, Bernardo

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 169 KB

english, 2011

2

Selective elimination of synovial inflammatory macrophages in rheumatoid arthritis by an Fcγ receptor I–directed immunotoxin

Joel A. G. Van Roon, Anneke J. Van Vuuren, Siska Wijngaarden, Kim M. G. Jacobs, Johannes W. J. Bijlsma, Floris P. J. G. Lafeber, Theo Thepen, Jan G. J. Van De Winkel

Journal:

Arthritis & Rheumatism

Année:

2003

Langue:

english

Fichier:

PDF, 156 KB

english, 2003

3

Regulation of immune response to inhaled antigen by alveolar macrophages: differential effects of in vivo alveolar macrophage elimination on the induction of tolerance vs. immunity

Theo Thepen, Christine McMenamin, Jane Oliver, Georg Kraal, Patrick G. Holt

Journal:

European Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 808 KB

english, 1991

4

In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA′ in a human acute myeloid leukemia xenograft tumor model

Mehmet Kemal Tur, Michael Huhn, Edgar Jost, Theo Thepen, Tim H. Brümmendorf, Stefan Barth

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 533 KB

english, 2011

5

A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

Markus Grewe, Carla A.F.M Bruijnzeel-Koomen, Erwin Schöpf, Theo Thepen, Alice G Langeveld-Wildschut, Thomas Ruzicka, Jean Krutmann

Journal:

Immunology Today

Année:

1998

Langue:

english

Fichier:

PDF, 137 KB

english, 1998

6

Interleukin 4 and interferon-γ expression of the dermal infiltrate in patients with erythroderma and mycosis fungoides. An immuno-histochemical study

Vigfús Sigurdsson, Johan Toonstra, Ilse C. Bihari, Carla A. F. M. Bruijnzeel-Koomen, Willem A. Van Vloten, Theo Thepen

Journal:

Journal of Cutaneous Pathology

Année:

2000

Langue:

english

Fichier:

PDF, 134 KB

english, 2000

7

Expression of VCAM-1, ICAM-1, E-selectin, and P-selectin on endothelium in situ in patients with erythroderma, mycosis fungoides and atopic dermatitis

Vigfús Sigurdsson, I. Jolanda M. De Vries, Johan Toonstra, Ilse C. Bihari, Theo Thepen, Carla A.F.M. Bruijnzeel-Koomen, Willem A. Van Vloten

Journal:

Journal of Cutaneous Pathology

Année:

2000

Langue:

english

Fichier:

PDF, 78 KB

english, 2000

8

Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein

Florian Kampmeier, Judith Niesen, Alexander Koers, Markus Ribbert, Andreas Brecht, Rainer Fischer, Fabian Kießling, Stefan Barth, Theo Thepen

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Année:

2010

Langue:

english

Fichier:

PDF, 491 KB

english, 2010

9

10.1038/71908

Thepen, Theo, van Vuuren, A. J. Hanneke, Kiekens, Rebecca C. M., Damen, Cora A., Vooijs, Wim C., van de Winkel, Jan G. J.

Journal:

Nature Biotechnology

Année:

2000

Langue:

english

Fichier:

PDF, 515 KB

english, 2000

10

Depletion of autoreactive B-lymphocytes by a recombinant myelin oligodendrocyte glycoprotein-based immunotoxin

Thomas Nachreiner, Florian Kampmeier, Theo Thepen, Rainer Fischer, Stefan Barth, Michael Stöcker

Journal:

Journal of Neuroimmunology

Année:

2008

Langue:

english

Fichier:

PDF, 682 KB

english, 2008

11

Recombinant soluble human Fcγ receptor I with picomolar affinity for immunoglobulin G

Antje Paetz, Markus Sack, Theo Thepen, Mehmet K. Tur, Daniela Bruell, Ricarda Finnern, Rainer Fischer, Stefan Barth

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 205 KB

english, 2005

12

Recombinant bispecific single chain antibody fragments induce Fcγ-receptor-mediated elimination of CD30+ lymphoma cells

Katharina Ranft, Theo Thepen, Rainer Fischer, Stefan Barth, Michael Stöcker

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 623 KB

english, 2009

13

Immunophenotyping of skin-infiltrating T-cell subsets in dogs with atopic dermatitis

Jacqueline D. Sinke, Theo Thepen, Ilse C. Bihari, Victor P.M.G. Rutten, Ton Willemse

Journal:

Veterinary Immunology and Immunopathology

Année:

1997

Langue:

english

Fichier:

PDF, 819 KB

english, 1997

14

Allergic inflammation in atopic dermatitis

Edward F. Knol, Elisabeth A. Langeveld, Frank C. van Reijsen, Theo Thepen, Piet L.B. Bruijnzeel, Carla A.F.M. Bruijnzeel-Koomen

Journal:

Journal of the European Academy of Dermatology and Venereology

Année:

1998

Langue:

english

Fichier:

PDF, 127 KB

english, 1998

15

In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model

Alessa Pardo, Michael Stöcker, Florian Kampmeier, Georg Melmer, Rainer Fischer, Theo Thepen, Stefan Barth

Journal:

Cancer Immunology, Immunotherapy

Année:

2012

Langue:

english

Fichier:

PDF, 534 KB

english, 2012

16

Increased specific IgE production in lungs after the induction of acute stress in rats☆☆☆★★★

Persoons, Jek H.A., Berkenbosch, Frank, Schornagel, Karin, Thepen, Theo, Kraal, Georg

Journal:

Journal of Allergy and Clinical Immunology

Année:

1995

Langue:

english

Fichier:

PDF, 859 KB

english, 1995

17

Nonspecific T-cell homing during inflammation in atopic dermatitis: Expression of cutaneous lymphocyte-associated antigen and integrin αEβ7 on skin-infiltrating T cells

de Vries, I.Jolanda M., Langeveld-Wildschut, Elisabeth G., van Reijsen, Frank C., Bihari, Ilse C., Bruijnzeel-Koomen, Carla A.F.M., Thepen, Theo

Journal:

Journal of Allergy and Clinical Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 2.09 MB

english, 1997

18

Clinical and immunologic variables in skin of patients with atopic eczema and either positive or negative atopy patch test reactions

Langeveld-Wildschut, Elisabeth G., Bruijnzeel, Piet L.B., Mudde, Geert C., Versluisa, Coraline, Van Ieperen-Van Dijka, Adrie G., Biharia, Ilse C., Knol, Edward F., Thepen, Theo, Bruijnzeel-Koomen, Car

Journal:

Journal of Allergy and Clinical Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 130 KB

english, 2000

19

Modulation of the atopy patch test reaction by topical corticosteroids and tar

Langeveld-Wildschut, Elisabeth G., Riedl, Hannes, Thepen, Theo, Biharia, Ilse C., Bruijnzeel, Piet L.B., Bruijnzeel-Koomen, Carla A.F.M.

Journal:

Journal of Allergy and Clinical Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 133 KB

english, 2000

20

267

Weyenbergh, Johan Van, Thepen, Theo, Soares, George, Khouri, Ricardo, Barth, Stefan, Silva-Santos, Gilvaneia, Costa, Jackson M., Barral, Aldina, Barral-Netto, Manoel

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 41 KB

english, 2013

21

Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins

Schiffer, Sonja, Rosinke, Reinhard, Jost, Edgar, Hehmann-Titt, Grit, Huhn, Michael, Melmer, Georg, Barth, Stefan, Thepen, Theo

Journal:

International Journal of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 688 KB

english, 2014

22

Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells

Schiffer, Sonja, Letzian, Soriba, Jost, Edgar, Mladenov, Radoslav, Hristodorov, Dmitrij, Huhn, Michael, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2013

23

Human microtubule-associated protein tau mediates targeted killing of CD30 + lymphoma cells in vitro and inhibits tumour growth in vivo

Hristodorov, Dmitrij, Nordlohne, Johannes, Mladenov, Radoslav, Huhn, Michael, Fischer, Rainer, Thepen, Theo, Barth, Stefan

Journal:

British Journal of Haematology

Année:

2014

Langue:

english

Fichier:

PDF, 364 KB

english, 2014

24

Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody

Hristodorov, Dmitrij, Mladenov, Radoslav, Brehm, Hannes, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 557 KB

english, 2014

25

Macrophages Play a Dual Role during Pulmonary Tuberculosis in Mice

Leemans, Jaklien C., Thepen, Theo, Weijer, Sebastiaan, Florquin, Sandrine, van Rooijen, Nico, van de Winkel, Jan G., van der Poll, Tom

Journal:

The Journal of Infectious Diseases

Année:

2005

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2005

26

Human Cytolytic Fusion Proteins: Modified Versions of Human Granzyme B and Angiogenin Have the Potential to Replace Bacterial Toxins in Targeted Therapies against CD64+ Diseases

Berges, Nina, Hehmann-Titt, Grit, Hristodorov, Dmitrij, Melmer, Georg, Thepen, Theo, Barth, Stefan

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 509 KB

english, 2014

27

Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages

Schiffer, Sonja, Hristodorov, Dmitrij, Mladenov, Radoslav, Aslanian, Eric, Huhn, Michael, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2013

28

Macrophage-Targeted Therapy: CD64-Based Immunotoxins for Treatment of Chronic Inflammatory Diseases

Hristodorov, Dmitrij, Mladenov, Radoslav, Huhn, Michael, Barth, Stefan, Thepen, Theo

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 500 KB

english, 2012

29

Labeling of Anti-MUC-1 Binding Single Chain Fv Fragments to Surface Modified Upconversion Nanoparticles for an Initial in Vivo Molecular Imaging Proof of Principle Approach

Hischemöller, Anja, Walter, Claudia, Weiler, Volker, Hummel, Helga, Thepen, Theo, Huhn, Michael, Barth, Stephan, Hoheisel, Werner, Köhler, Karen, Dimova-Landen, Diana, Bremer, Christoph, Haase, Markus

Journal:

International Journal of Molecular Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 425 KB

english, 2012

30

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies

Hristodorov, Dmitrij, Mladenov, Radoslav, von Felbert, Verena, Huhn, Michael, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 693 KB

english, 2015

31

Fully-human MAP-fusion protein selectively targets and eliminates proliferating CD64+ M1 macrophages

Hristodorov, Dmitrij, Mladenov, Radoslav, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Immunology & Cell Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2016

32

CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases

Akinrinmade, Olusiji A., Chetty, Shivan, Daramola, Adebukola K., Islam, Mukit-ul, Thepen, Theo, Barth, Stefan

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2017